Searchable abstracts of presentations at key conferences in endocrinology

ea0070aep744 | Pituitary and Neuroendocrinology | ECE2020

Pasireotide-induced hyperglycemia and efficacy of antidiabetic treatments in patients with acromegaly: Evaluation of two referral centers

F.S. Grasso Ludovica , Chiloiro Sabrina , Pirchio Rosa , Giampietro Antonella , Auriemma Renata S. , Bianchi Antonio , De Martino Maria Cristina , Negri Mariarosaria , Colao Annamaria , Pontecorvi Alfredo , De Marinis Laura , Pivonello Rosario

Pasireotide (PAS) has a safety profile similar to first-generationsomatostatin analogues (SSA), except for a higher frequency of hyperglycaemia-related adverse events (AEs). However, consensus on the best management of PAS-induced hyperglycaemia in acromegalic patients has still to be defined. The current study aims at investigating the effects of long-term PAS treatment on glucose metabolism, by evaluating the clinical management of hyperglycemia-relatedAEs in acromegalic pat...